BDBM50181247 5-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(naphthalen-1-yl)-2,4-dioxoimidazolidin-1-yl)methyl)-2-(methylsulfonyl)benzonitrile::CHEMBL380615

SMILES CC1(N(Cc2ccc(c(c2)C#N)S(C)(=O)=O)C(=O)N(CCCn2ccnc2)C1=O)c1cccc2ccccc12

InChI Key InChIKey=YREMCUVJCPALAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181247   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181247(5-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed