BDBM50181933 2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL205598

SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OC(c2ccc(F)cc2)c2ccc(F)cc2)cc1

InChI Key InChIKey=SOPBXOVESODUSC-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50181933   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against HCV 1b NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against HCV 1a NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of HCV RNA replication in Huh5-2 cells after 48 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181933(2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed