BDBM50182092 4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)propyl)piperidin-4-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL201461
SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2ccccc12)-c1ccc(cc1)C(F)(F)F
InChI Key InChIKey=AMSFCNUCSFWCJW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50182092
TargetCathepsin S(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson And Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair