BDBM50182135 3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroisoxazole::CHEMBL208485

SMILES COc1c(ccc2occc12)C1=NOC(C1)c1ccccc1

InChI Key InChIKey=USHIACGOJWXTMQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182135   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50182135(3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroi...)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50182135(3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroi...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenylphosphate as substrate after 10 minMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50182135(3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroi...)
Affinity DataIC50:  2.27E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed