BDBM50182399 CHEMBL3818479

SMILES Cc1nccn(-c2ccc(c(Cl)c2)-c2cc3cnc(NC4COC4)nc3n(CC3CCNCC3(F)F)c2=O)c1=O

InChI Key InChIKey=SNHDCUDTVCJVGD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182399   

TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50182399(CHEMBL3818479)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50182399(CHEMBL3818479)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50182399(CHEMBL3818479)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed