BDBM50184438 2,4-dichloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine::CHEMBL383451

SMILES CN1CCc2ccccc2Cc2cc(Cl)c(O)c(Cl)c2CC1

InChI Key InChIKey=WPJVKYVAARSXKN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50184438   

TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184438(2,4-dichloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexah...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of D5 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184438(2,4-dichloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexah...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]SCH 23390 from D1 dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184438(2,4-dichloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexah...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184438(2,4-dichloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexah...)
Affinity DataKi:  37.5nMAssay Description:Inhibition of D2L dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184438(2,4-dichloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexah...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]spiperone from D2L dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed