BDBM50184492 5-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzo[d]imidazole::CHEMBL204139
SMILES C1Cc2c(c(nn2C1)-c1ccccn1)-c1ccc2nc[nH]c2c1
InChI Key InChIKey=SVBDCIYLLHNPPR-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50184492
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human TGFbeta R1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 422nMAssay Description:Inhibition of TGFbeta R1 induced transcriptional activation of p3TP-Lux in mink Mv1Lu lung cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.73E+3nMAssay Description:Inhibition of recombinant human TGFbeta R2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of MLK7More data for this Ligand-Target Pair