BDBM50184496 CHEMBL441176::dimethyl-(3-{6-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-benzoimidazol-1-yl}-propyl)-amine
SMILES CN(C)CCCn1cnc2ccc(cc12)-c1c2CCCn2nc1-c1cccc(C)n1
InChI Key InChIKey=OSOLSDDKICGWFS-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50184496
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of MLK7More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human TGFbeta R1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human TGFbeta R2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of TGFbeta R1 induced transcriptional activation of p3TP-Lux in mink Mv1Lu lung cellsMore data for this Ligand-Target Pair