BDBM50184730 4-(trifluoromethyl)-N-(4-(3-(trifluoromethyl)pyridin-2-yl)phenyl)benzamide::CHEMBL209113

SMILES FC(F)(F)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ncccc1C(F)(F)F

InChI Key InChIKey=FPKZLONASYLHRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184730   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50184730(4-(trifluoromethyl)-N-(4-(3-(trifluoromethyl)pyrid...)
Affinity DataIC50:  33nMpH: 5.5Assay Description:Inhibition of acidic pH 5.5-stimulated current in CHO cells expressing human TRPV1 receptor by patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50184730(4-(trifluoromethyl)-N-(4-(3-(trifluoromethyl)pyrid...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed