BDBM50184879 CHEMBL424676::dimethyl-{2-[(4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-2-pyridinyl}phenyl)oxy]ethyl}amine
SMILES CN(C)CCOc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1
InChI Key InChIKey=VYTQMUCONGRNBX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50184879
Affinity DataIC50: 15nMAssay Description:Displacement of rhodamine green fluorescently labeled ATP from recombinant GST-ALK5 by FP assayMore data for this Ligand-Target Pair
TargetTransforming growth factor beta-1 proprotein(Homo sapiens (Human))
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...More data for this Ligand-Target Pair