BDBM50184886 2-[4-(trifluoromethyl)phenyl]-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine::4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)-2-(4-(trifluoromethyl)phenyl)pyridine::CHEMBL383523

SMILES FC(F)(F)c1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key InChIKey=JUJSXTHOUVCQGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184886   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184886(2-[4-(trifluoromethyl)phenyl]-4-(3-pyridin-2-yl-1H...)
Affinity DataIC50:  24nMAssay Description:Displacement of rhodamine green fluorescently labeled ATP from recombinant GST-ALK5 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184886(2-[4-(trifluoromethyl)phenyl]-4-(3-pyridin-2-yl-1H...)
Affinity DataIC50:  24nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed