BDBM50184901 2-(4-fluorophenyl)-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridine::2-[4-fluorophenyl]-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine::CHEMBL381948

SMILES Fc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key InChIKey=HZJPBOLTWHOKEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184901   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184901(2-(4-fluorophenyl)-4-(3-(pyridin-2-yl)-1H-pyrazol-...)
Affinity DataIC50:  48nMAssay Description:Displacement of rhodamine green fluorescently labeled ATP from recombinant GST-ALK5 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50184901(2-(4-fluorophenyl)-4-(3-(pyridin-2-yl)-1H-pyrazol-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed