BDBM50185405 (+/-)-(4aS,6R,8aS)-6-(4-chloro-benzenesulfonyl)-3-cyclobutyl-6-(2,5-difluoro-phenyl)-octahydro-benzo[1,2,6]thiadiazine 2,2-dioxide::CHEMBL378502

SMILES Fc1ccc(F)c(c1)[C@]1(CC[C@@H]2NS(=O)(=O)N(C[C@@H]2C1)C1CCC1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=QJVCGYBQNGBULL-UQDCGMOVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185405   

LigandPNGBDBM50185405((+/-)-(4aS,6R,8aS)-6-(4-chloro-benzenesulfonyl)-3-...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of gamma secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed