BDBM50187438 (Z)-1-(5-(prop-1-enyloxy)pyridin-3-yl)-1,4-diazepane::CHEMBL209080::cis-1-(5-propen-1-yloxypyridin-3-yl)-[1,4]diazepane
SMILES C\C=C/Oc1cncc(c1)N1CCCNCC1
InChI Key InChIKey=GQUWFILFBVDMRP-WAPJZHGLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50187438
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataEC50: 2.09E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Neurosearch
Curated by ChEMBL
Neurosearch
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 1.29nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair