BDBM50187728 CHEMBL3828585

SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2CCCCc2c1

InChI Key InChIKey=KJIJROQSYYMIGX-FXRZFVDSSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187728   

Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187728(CHEMBL3828585)
Affinity DataIC50:  500nMAssay Description:Inhibition of 6x-His-tagged Staphylococcus aureus diapophytoene desaturase expressed in Escherichia coli BL21 (DE3) using diapophytoene substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187728(CHEMBL3828585)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of diapophytoene desaturase in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin pigment formation after 48 hrs by spe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187728(CHEMBL3828585)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant human ERG expressed in CHO cells at -80 mV holding potential measured after 3 minutes by automated whole cell patch clamp Q...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187728(CHEMBL3828585)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187728(CHEMBL3828585)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells after 3 mins at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed