BDBM50188055 1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine::CHEMBL213754

SMILES CCCOc1ccccc1CC(N1CCNCC1)c1ccccc1

InChI Key InChIKey=PSIGDYKJTYBHDY-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50188055   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188055(1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine | ...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188055(1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine | ...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188055(1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine | ...)
Affinity DataKi:  1.95E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188055(1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine | ...)
Affinity DataIC50:  31nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188055(1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine | ...)
Affinity DataIC50:  5.84E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188055(1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine | ...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed