BDBM50188087 1-(4-methyl-benzyl)-1H-imidazole::1-(4-methylbenzyl)-1H-imidazole::CHEMBL212741

SMILES Cc1ccc(Cn2ccnc2)cc1

InChI Key InChIKey=DQXGQHAFADWCKG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188087   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188087(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)
Affinity DataIC50:  5.06E+4nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188087(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)
Affinity DataIC50:  8.81E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50188087(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50188087(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)
Affinity DataIC50:  258nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188087(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)
Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed