BDBM50188374 1-phenyl-8-(2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL377140
SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCC1c1ccccc1
InChI Key InChIKey=XMWPUEPUQVYCIC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50188374
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 1.20E+4nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [3H]NOP from human NOP receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 26nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1 by radiometric assayMore data for this Ligand-Target Pair