BDBM50189998 CHEMBL385471::N-(5-chloro-2-fluorophenyl)-7-methoxy-6-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine

SMILES COc1cc2ncnc(Nc3cc(Cl)ccc3F)c2cc1OCC1CCN(C)CC1

InChI Key InChIKey=JARRHXQJNGEMMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189998   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189998(CHEMBL385471 | N-(5-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed