BDBM50190653 CHEMBL3959689

SMILES [H][C@@]12[C@@H](OC(C)=O)[C@]3(OC1(C)C)[C@H](C)CC[C@H](OC(C)=O)[C@@]3(C)[C@H](OC(=O)c1ccccc1)[C@@H]2OC(C)=O

InChI Key InChIKey=ZFYHVMQCJIKTLP-OTOYSWGPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190653   

TargetLarge neutral amino acids transporter small subunit 3(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50190653(CHEMBL3959689)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of LAT3 in human LNCAP cells assessed as inhibition of [3H]L-leucine uptake after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50190653(CHEMBL3959689)
Affinity DataIC50:  200nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50190653(CHEMBL3959689)
Affinity DataIC50: <8nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed