BDBM50191365 Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-carbamoyloxy-3,10-dihydroxy-9,15-dimethoxy-7,11,13,19-tetramethyl-21-oxa-23-aza-tricyclo[18.2.1.0*5,22*]tricosa-1,3,5(22),12,16,18,20(23)-heptaen-4-yl)-ammonium chloride::CHEMBL377782

SMILES CO[C@H]1C[C@H](C)Cc2c([NH2+]CC=C)c(O)cc3nc(oc23)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O

InChI Key InChIKey=AMSRVKNAPILVBD-HJBRVBGESA-O

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50191365   

TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191365(Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-ca...)
Affinity DataEC50:  435nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191365(Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-ca...)
Affinity DataEC50:  585nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191365(Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-ca...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191365(Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-ca...)
Affinity DataEC50:  3.23E+3nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed