BDBM50191367 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride::Allyl-((4E,6Z,10E)-(8S,9S,12S,13R,14S,16R)-9-carbamoyloxy-13,20,22-trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-2-aza-bicyclo[16.3.1]docosa-1(22),4,6,10,18,20-hexaen-19-yl)-ammonium chloride::CHEMBL377559
SMILES CO[C@H]1C[C@H](C)Cc2c(O)c(NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)cc(O)c2[NH2+]CC=C
InChI Key InChIKey=OAKGNIRUXAZDQF-QJJDEUMOSA-O
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50191367
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals
Curated by ChEMBL
Infinity Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 27nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 119nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals
Curated by ChEMBL
Infinity Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals
Curated by ChEMBL
Infinity Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals
Curated by ChEMBL
Infinity Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 307nMAssay Description:Inhibition of Hsp90 in human MM1S cells by BODIPY-AG fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of imatinib-resistant PDGFR D842V mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 h...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of imatinib-resistant PDGFR D842V mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 h...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals
Curated by ChEMBL
Infinity Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 307nMAssay Description:Inhibition of Hsp90 in human MM1S cells by BODIPY-AG fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals
Curated by ChEMBL
Infinity Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair