BDBM50191463 CHEMBL378467::methyl (2S)-2-[(2R)-2-[(2S)-2-{4-[(7-{3-[(1-{[1-(carbamoylmethyl)-2-oxo-1,2-dihydropyridin-3-yl]carbamoyl}-2-methylpropyl)carbamoyl]propoxy}naphthalen-2-yl)oxy]butanamido}-3-methylbutanamido]-4-methylpentanamido]-3-methylbutanoate

SMILES COC(=O)[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)CCCOc1ccc2ccc(OCCCC(=O)NC(C(C)C)C(=O)Nc3cccn(CC(N)=O)c3=O)cc2c1)C(C)C)C(C)C

InChI Key InChIKey=ZHIXFGDQBWKSNP-ZZUWNNGMSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50191463   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50191463(CHEMBL378467 | methyl (2S)-2-[(2R)-2-[(2S)-2-{4-[(...)
Affinity DataKi:  100nMAssay Description:Inhibition of dimerization of HIV1 protease 150V mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50191463(CHEMBL378467 | methyl (2S)-2-[(2R)-2-[(2S)-2-{4-[(...)
Affinity DataKi:  200nMAssay Description:Inhibition of dimerization of HIV1 protease ANAM-11 mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50191463(CHEMBL378467 | methyl (2S)-2-[(2R)-2-[(2S)-2-{4-[(...)
Affinity DataKi:  240nMAssay Description:Inhibition of dimerization of HIV1 protease V82A mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50191463(CHEMBL378467 | methyl (2S)-2-[(2R)-2-[(2S)-2-{4-[(...)
Affinity DataKi:  400nMAssay Description:Inhibition of wild type HIV1 protease dimerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50191463(CHEMBL378467 | methyl (2S)-2-[(2R)-2-[(2S)-2-{4-[(...)
Affinity DataKi:  500nMAssay Description:Inhibition of dimerization of HIV1 protease D30N mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50191463(CHEMBL378467 | methyl (2S)-2-[(2R)-2-[(2S)-2-{4-[(...)
Affinity DataKi:  500nMAssay Description:Inhibition of dimerization of HIV1 protease G48V/L90M mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50191463(CHEMBL378467 | methyl (2S)-2-[(2R)-2-[(2S)-2-{4-[(...)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of dimerization of HIV1 protease MDR-HM mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed