BDBM50191533 2-[4-(4'-chloro-4-dimethylcarbamoylbiphenyl-2-ylmethoxy)-2-fluorophenyl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid::CHEMBL378026
SMILES CN(C)C(=O)c1ccc(c(COc2ccc(-c3nc4cc(ccc4n3C3CCCCC3)C(O)=O)c(F)c2)c1)-c1ccc(Cl)cc1
InChI Key InChIKey=LAPUEQHNBGENHI-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50191533
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.34E+7nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
Affinity DataIC50: 8.33E+7nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair