BDBM50192518 1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-phenylurea::CHEMBL216192
SMILES Cc1ccc(Oc2ccc(cc2NC(=O)Nc2ccccc2)C(=O)NCCN2CCCC2)cc1C
InChI Key InChIKey=AENNLOUNPCFAFV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50192518
Affinity DataKi: 2nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Activity at human MCHR1 expressed in CHOK1-Gqi cells assessed as inhibition of MCH-induced calcium ion release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Activity at rat MCHR1 expressed in CHOK1-Gqi cells assessed as inhibition of MCH-induced calcium ion release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Activity at mouse MCHR1 expressed in CHOK1-Gqi cells assessed as inhibition of MCH-induced calcium ion release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Antagonist activity at MCHR1 by Schild experimentMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPAMore data for this Ligand-Target Pair