BDBM50192764 CHEMBL3934882
SMILES C[C@H]1COC(=O)Nc2ccc(C3CC3)c(CN(C)C(=O)[C@H](Nc3ccc4c(N)ncc(F)c4c3)c3ccc1c(C)c3)c2
InChI Key InChIKey=YBLXUAHRYXEFCL-WWOZWPLTSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50192764
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of human kallikrein1 at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of recombinant human TF-factor 7a using factor 10 as substrate at 37 degCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Inhibition of activated protein C (unknown origin) at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of factor 10a (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of thrombin (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair