BDBM50193093 RGB-286638

SMILES COCCN1CCN(Cc2ccc(cc2)-c2n[nH]c3-c4cccc(NC(=O)NN5CCOCC5)c4C(=O)c23)CC1

InChI Key InChIKey=XLSYZSRXVVCHLS-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50193093   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant CDK4/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  5nMAssay Description:Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal stripsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 3/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK3/cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  1nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  1nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  1nMAssay Description:Ability to displace [3H]glycine from strychnine-insensitive glycine receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  4nMAssay Description:Ability to displace [3H]glycine from strychnine-insensitive glycine receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparationsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  3nMAssay Description:Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal stripsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193093(RGB-286638)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed