BDBM50193790 6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-yl)methoxy)nicotinonitrile::CHEMBL384650

SMILES CC1(C)C(COc2ccc(cn2)C#N)CN(C2CCCCCC2)C1=O

InChI Key InChIKey=IIOIWTHGGFXVPM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50193790   

Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193790(6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-y...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193790(6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-y...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193790(6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-y...)
Affinity DataIC50:  62nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193790(6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-y...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed