BDBM50194461 7-amino-5-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)-1,6-naphthyridin-2(1H)-one::7-amino-5-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)quinolin-2(1H)-one::CHEMBL219804

SMILES Nc1cc2n(-c3c(F)cccc3F)c(=O)ccc2c(n1)-c1ccc(F)cc1F

InChI Key InChIKey=RVTPPRYTUBCENU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194461   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194461(7-amino-5-(2,4-difluorophenyl)-1-(2,6-difluorophen...)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of labeled MK-499 from human ERG in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194461(7-amino-5-(2,4-difluorophenyl)-1-(2,6-difluorophen...)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of p38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194461(7-amino-5-(2,4-difluorophenyl)-1-(2,6-difluorophen...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of mouse p38alpha after 3 hrs by SPA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed