BDBM50194613 CHEMBL3947764
SMILES FC(F)(F)c1c(CN2CCC(CC2)c2ccccc2)ccn2c(CC3CC3)nnc12
InChI Key InChIKey=LYDKDODJIBQNLK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50194613
Affinity DataKi: 7.60nMAssay Description:Displacement of [3H]JNJ-46281222 from human mGlu2 receptor expressed in CHOK1 cell membranes after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Displacement of [3H]JNJ-46281222 from human mGlu2 receptor expressed in CHOK1 cell membranes preincubated for 3 hrs followed by [3H]JNJ-46281222 addi...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Positive allosteric modulator activity at mGluR2 receptor (unknown origin) assessed as glutamate-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHOK1 cell membranes assessed as increase in glutamate-induced [35S]GTPgammaS bin...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHO cell membranes assessed as potentiation of glutamate-induced effect incubated...More data for this Ligand-Target Pair