BDBM50194865 CHEMBL218194::N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(isopropylamino)picolinamide

SMILES CC(C)Nc1nc(cc(N)c1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=CTQXMPOHMBPPMC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194865   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194865(CHEMBL218194 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  84nMAssay Description:Inhibition of JNK2 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50194865(CHEMBL218194 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  67.0nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50194865(CHEMBL218194 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  67nMAssay Description:Inhibition of JNK1 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed