BDBM50194874 CHEMBL218219::N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(2-hydroxyethylamino)picolinamide

SMILES CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(NCCO)n2)cc1

InChI Key InChIKey=KLYSOWZEHKSGHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194874   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194874(CHEMBL218219 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  150nMAssay Description:Inhibition of JNK2 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50194874(CHEMBL218219 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  92.9nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50194874(CHEMBL218219 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  93nMAssay Description:Inhibition of JNK1 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed