BDBM50194878 3-(6-((4-(methylsulfonyl)benzyl)carbamoyl)-4-amino-3-cyanopyridin-2-yl)acrylic acid::CHEMBL434368

SMILES CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(\C=C\C(O)=O)n2)cc1

InChI Key InChIKey=AMAYXMZTQTYOQN-VOTSOKGWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194878   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194878(3-(6-((4-(methylsulfonyl)benzyl)carbamoyl)-4-amino...)
Affinity DataIC50:  300nMAssay Description:Inhibition of JNK1 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194878(3-(6-((4-(methylsulfonyl)benzyl)carbamoyl)-4-amino...)
Affinity DataIC50:  300nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194878(3-(6-((4-(methylsulfonyl)benzyl)carbamoyl)-4-amino...)
Affinity DataIC50:  430nMAssay Description:Inhibition of JNK2 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed