BDBM50194964 2-ethoxy-2-((6-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyridin-3-yl)methyl)butanoic acid::CHEMBL218950

SMILES CCOC(CC)(Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)nc1)C(O)=O

InChI Key InChIKey=NZZMRMMECJETRO-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194964   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50194964(2-ethoxy-2-((6-(2-(5-methyl-2-phenyloxazol-4-yl)et...)
Affinity DataKi:  1.44E+4nMAssay Description:Displacement of radiolabeled darglitazone from human PPAR gamma by SPA binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50194964(2-ethoxy-2-((6-(2-(5-methyl-2-phenyloxazol-4-yl)et...)
Affinity DataEC50:  1.51E+4nMAssay Description:Displacement of radiolabeled GW2331 from human PPAR alpha by SPA binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50194964(2-ethoxy-2-((6-(2-(5-methyl-2-phenyloxazol-4-yl)et...)
Affinity DataEC50:  4.67E+3nMAssay Description:Agonist activity at human PPAR alpha in a HepG2 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50194964(2-ethoxy-2-((6-(2-(5-methyl-2-phenyloxazol-4-yl)et...)
Affinity DataEC50:  2.81E+3nMAssay Description:Agonist activity at human PPAR gamma in a HepG2 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed