BDBM50195178 2-chloro-6-fluoro-N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamide::CHEMBL223743

SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2c(F)cccc2Cl)(CC1)C(=O)N1CCOCC1

InChI Key InChIKey=YCYMPOZYBIQGNA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50195178   

TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50195178(2-chloro-6-fluoro-N-((4-(morpholine-4-carbonyl)-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Merck And

Curated by ChEMBL
LigandPNGBDBM50195178(2-chloro-6-fluoro-N-((4-(morpholine-4-carbonyl)-1-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of rat GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50195178(2-chloro-6-fluoro-N-((4-(morpholine-4-carbonyl)-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human TauTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Mus musculus)
Merck And

Curated by ChEMBL
LigandPNGBDBM50195178(2-chloro-6-fluoro-N-((4-(morpholine-4-carbonyl)-1-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of mouse GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50195178(2-chloro-6-fluoro-N-((4-(morpholine-4-carbonyl)-1-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed