BDBM50195663 CHEMBL217658::N-cyclopropylmethyl-14beta-[2'-(4''-chlorophenyl)-ethanamino]-7,8-dihydronormorphinone

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NCCc1ccc(Cl)cc1

InChI Key InChIKey=AXLHFOFZVNWFHI-HBMTYJCASA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50195663   

TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50195663(CHEMBL217658 | N-cyclopropylmethyl-14beta-[2'-(4''...)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50195663(CHEMBL217658 | N-cyclopropylmethyl-14beta-[2'-(4''...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]U-69593 from human recombinant kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50195663(CHEMBL217658 | N-cyclopropylmethyl-14beta-[2'-(4''...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]Cl-DPDPE from human recombinant delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50195663(CHEMBL217658 | N-cyclopropylmethyl-14beta-[2'-(4''...)
Affinity DataIC50:  0.340nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50195663(CHEMBL217658 | N-cyclopropylmethyl-14beta-[2'-(4''...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50195663(CHEMBL217658 | N-cyclopropylmethyl-14beta-[2'-(4''...)
Affinity DataIC50:  1.60nMAssay Description:Activity at human recombinant delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed