BDBM50195666 CHEMBL443311::N-cyclopropylmethyl-14beta-[3'-(4'-chlorophenyl)propylamino]-7,8-dihydronormorphinone
SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NCCCc1ccc(Cl)cc1
InChI Key InChIKey=ZHVLHUNBLJWDPM-ZLPBPMGLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50195666
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]Cl-DPDPE from delta receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol
Curated by ChEMBL
University Of Bristol
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Activity at human recombinant delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0125nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00600nMAssay Description:Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair