BDBM50195819 CHEMBL3818089

SMILES COc1cc(\C=C\C(=O)NCCC2CCN(Cc3ccccc3)CC2)ccc1O

InChI Key InChIKey=MDBSJGXOQHYGEI-CSKARUKUSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50195819   

TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50195819(CHEMBL3818089)
Affinity DataIC50:  76nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured for 5 mins by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50195819(CHEMBL3818089)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate incubated for 15 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Indian Institute Of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50195819(CHEMBL3818089)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of equine serum BuChE preincubated for 5 mins followed by substrate addition using S-butyrylthiocholine iodide as substrate by Ellman's me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50195819(CHEMBL3818089)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate incubated for 15 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute Of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50195819(CHEMBL3818089)
Affinity DataIC50:  650nMAssay Description:Inhibition of electric eel AChE preincubated for 5 mins followed by substrate addition using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50195819(CHEMBL3818089)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed