BDBM50196585 CHEMBL252754::N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-phenylbutan-2-yl)-4-(isopentylsulfonyl)butanamide

SMILES COc1cccc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)CCCS(=O)(=O)CCC(C)C)c1

InChI Key InChIKey=HANOKGOIMNNZGY-IZZNHLLZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196585   

TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196585(CHEMBL252754 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196585(CHEMBL252754 | N-((2S,3R)-4-(3-methoxybenzylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed