BDBM50197297 CHEMBL3928799::ebselen derivative 2d

SMILES Oc1ccccc1NC(=O)c1ccccc1[Se][Se]c1ccccc1C(=O)Nc1ccccc1O

InChI Key InChIKey=KWHUYBHCJSYTIT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197297   

TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50197297(CHEMBL3928799 | ebselen derivative 2d)
Affinity DataIC50:  5.44E+3nMAssay Description:Non-covalent/mixed type inhibition of recombinant human MetAP2 using Met-AMC as substrate preincubated for 30 mins followed by substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The State University Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50197297(CHEMBL3928799 | ebselen derivative 2d)
Affinity DataIC50:  339nMAssay Description:Inhibition of SARS-CoV-2 papain-like protease preincubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The State University Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50197297(CHEMBL3928799 | ebselen derivative 2d)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of recombinant SARS CoV-2 PL protease incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The State University Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50197297(CHEMBL3928799 | ebselen derivative 2d)
Affinity DataIC50:  339nMAssay Description:The inhibitor was screened against recombinant PL​pro​SARS and PL​pro​CoV2 at 37°Cin the assay buffer as described above. For...More data for this Ligand-Target Pair
In DepthDetails