BDBM50198016 (2E)-N-[3-(dimethylamino)propyl]-3-[16-(hydroxymethyl)-5-oxo-4,14,18-triazaheptacyclo[12.10.2.0^{2,6}.0^{7,26}.0^{8,13}.0^{18,25}.0^{19,24}]hexacosa-1(25),2(6),7(26),8(13),9,11,19,21,23-nonaen-10-yl]prop-2-enamide::CHEMBL233856

SMILES CN(C)CCCNC(=O)\C=C\c1ccc2n3CC(CO)Cn4c5ccccc5c5c6CNC(=O)c6c(c2c1)c3c45

InChI Key InChIKey=OPRAUJGAKIICCS-PKNBQFBNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198016   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50198016((2E)-N-[3-(dimethylamino)propyl]-3-[16-(hydroxymet...)
Affinity DataIC50:  237nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed