BDBM50198791 7-(2,6-dimethylphenyl)-5-methyl-N-(2-(2-(pyrrolidin-1-yl)ethoxy)pyridin-4-yl)benzo[e][1,2,4]triazin-3-amine::CHEMBL437004::US8481536, 388::US8481536, 584

SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccnc(OCCN4CCCC4)c3)nnc2c1

InChI Key InChIKey=YHHHJKZCRBUOTD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198791   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198791(7-(2,6-dimethylphenyl)-5-methyl-N-(2-(2-(pyrrolidi...)
Affinity DataIC50:  5.60nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198791(7-(2,6-dimethylphenyl)-5-methyl-N-(2-(2-(pyrrolidi...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198791(7-(2,6-dimethylphenyl)-5-methyl-N-(2-(2-(pyrrolidi...)
Affinity DataIC50:  128nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent