BDBM50198805 5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazin-3-amine::7-phenyl-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-benzotriazin-::CHEMBL230685::US8481536, 524::US8481536, 615

SMILES Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)-c1ccccc1

InChI Key InChIKey=ZUMICAGHFTUJTI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50198805   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  341nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  111nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  391nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  530nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  340nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  341nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed