BDBM50200037 2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-yl)-N-(m-tolyl)acetamide::CHEMBL375596
SMILES Cc1cccc(NC(=O)CN2CCC(CC2)c2ccccn2)c1
InChI Key InChIKey=JFCDMGGMCUKHST-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50200037
Affinity DataKi: 4nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D4.4 receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting me...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]A369508 from human D4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting me...More data for this Ligand-Target Pair
Affinity DataKi: 167nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D3 receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 251nMAssay Description:Displacement of [3H](R)-(+)-7-OH-DPAT from human D2L receptor expressed in HEK293 cell membranes measured after 90 mins by scintillation counting met...More data for this Ligand-Target Pair
Affinity DataKi: 1.68E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Displacement of [125I]7-OH-PIPAT from human D2L receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6.25E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
Affinity DataIC50: 5.85E+3nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured afte...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human D3 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...More data for this Ligand-Target Pair
Affinity DataEC50: 473nMAssay Description:Agonist activity at human D4 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by luminesce...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human D3 receptor expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by luminesce...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...More data for this Ligand-Target Pair