BDBM50200932 (3S)-3-[(2S)-6-(6-{5-[(3aS,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanamido)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-carboxybutanamido]hexanamido]-5-[(2,6-dimethylphenyl)carbonyloxy]-4-oxopentanoic acid::CHEMBL221870

SMILES Cc1cccc(C)c1C(=O)OCC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)CCCCCNC(=O)CCCCC1SC[C@@H]2NC(=O)N[C@H]12)NC(=O)[C@H](CCC(O)=O)NC(=O)OCc1ccccc1

InChI Key InChIKey=DOBIYIOPZIMMRH-AMBBWHSESA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50200932   

TargetCaspase-1(Homo sapiens (Human))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50200932((3S)-3-[(2S)-6-(6-{5-[(3aS,6aR)-2-oxo-hexahydro-1H...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of human caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50200932((3S)-3-[(2S)-6-(6-{5-[(3aS,6aR)-2-oxo-hexahydro-1H...)
Affinity DataKi:  540nMAssay Description:Inhibition of human caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50200932((3S)-3-[(2S)-6-(6-{5-[(3aS,6aR)-2-oxo-hexahydro-1H...)
Affinity DataKi:  840nMAssay Description:Inhibition of human caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50200932((3S)-3-[(2S)-6-(6-{5-[(3aS,6aR)-2-oxo-hexahydro-1H...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human caspase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-2(Homo sapiens (Human))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50200932((3S)-3-[(2S)-6-(6-{5-[(3aS,6aR)-2-oxo-hexahydro-1H...)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of human caspase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50200932((3S)-3-[(2S)-6-(6-{5-[(3aS,6aR)-2-oxo-hexahydro-1H...)
Affinity DataKi:  5.50E+5nMAssay Description:Inhibition of human caspase 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed