BDBM50201087 1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]-3,5-dimethyl-1H-pyridin-4-one::CHEMBL219015

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cn1cc(C)c(=O)c(C)c1)C(F)(F)F

InChI Key InChIKey=JTIJBQLFJJJIJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201087   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201087(1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to MR by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201087(1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of tetramethylrhodamine labeled RU486 binding to PR by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201087(1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50:  120nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed