BDBM50201375 CHEMBL240643::N-(4-isopropylphenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-pyrazole-5-carboxamide

SMILES CC(C)c1ccc(NC(=O)c2c(NCc3ccncc3)cnn2C)cc1

InChI Key InChIKey=DLYDQCVZBQEHHR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201375   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201375(CHEMBL240643 | N-(4-isopropylphenyl)-1-methyl-4-(p...)
Affinity DataIC50:  290nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201375(CHEMBL240643 | N-(4-isopropylphenyl)-1-methyl-4-(p...)
Affinity DataIC50:  88nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201375(CHEMBL240643 | N-(4-isopropylphenyl)-1-methyl-4-(p...)
Affinity DataIC50:  440nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed