BDBM50202245 CHEMBL3909397
SMILES COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)c4c(OCc5cccc(Br)c5)cccc4o3)c2c1
InChI Key InChIKey=IHXYENWQRGTOHE-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50202245
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Univ. Grenoble Alpes
Curated by ChEMBL
Univ. Grenoble Alpes
Curated by ChEMBL
Affinity DataEC50: 5.40E+8nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as increase in mitoxantrone accumulation incubated for 30 mins by flow cytome...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Univ. Grenoble Alpes
Curated by ChEMBL
Univ. Grenoble Alpes
Curated by ChEMBL
Affinity DataEC50: 540nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair