BDBM50202245 CHEMBL3909397

SMILES COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)c4c(OCc5cccc(Br)c5)cccc4o3)c2c1

InChI Key InChIKey=IHXYENWQRGTOHE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202245   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50202245(CHEMBL3909397)
Affinity DataEC50:  5.40E+8nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as increase in mitoxantrone accumulation incubated for 30 mins by flow cytome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50202245(CHEMBL3909397)
Affinity DataEC50:  540nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed