BDBM50202298 (R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benzo[cd]pyren-2-one::CHEMBL253318
SMILES CN1CCc2ccc3[nH]c(=O)c4cccc5C[C@@H]1c2c3c45
InChI Key InChIKey=GTFWUPYRBYXCRC-CQSZACIVSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50202298
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Displacement of [3H]5-HT from rat SERTMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Binding affinity at 5HT7 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Displacement of [3H]8-OH-DPAT from rat 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 341nMAssay Description:In vitro binding affinity of the compound towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]-5-HT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 373nMAssay Description:In vitro binding affinity of the compound towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [...More data for this Ligand-Target Pair
Affinity DataKi: 6.11E+3nMAssay Description:In vitro binding affinity of the compound towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair