BDBM50202333 (R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-benzo[cd]pyren-1-one::CHEMBL253319

SMILES CN1CCc2ccc3c4c2[C@H]1Cc1cccc([nH]c3=O)c41

InChI Key InChIKey=DTLGJDYEVFKDLJ-CQSZACIVSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50202333   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  55nMAssay Description:In vitro binding affinity of the compound towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  55nMAssay Description:In vitro binding affinity of the compound towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]-5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  178nMAssay Description:In vitro binding affinity of the compound towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]5-HT from rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  370nMAssay Description:Displacement of [3H]8-OH-DPAT from rat 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  6.10E+3nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed